School of Chemistry and Biochemistry
Georgia Institute of Technology
Bachelor of Pharmacy, Kathmandu University, Nepal
Masters in Chemistry, University of Alabama, Huntsville, USA
I graduated from Kathmandu University, Nepal with a Bachelor’s degree in pharmacy working under Dr. Panna Thapa and Dr. Uttam Budathoki on formulation and in-vitro evaluation of lyophilized dry emulsion tablets for mucosal flash delivery of drugs. My master’s degree is in organic chemistry where I worked under Dr. William N. Setzer at University of Alabama, Huntsville towards natural products isolation and computational organic chemistry. I moved to University of Texas, San Antonio for a year as a postmaster researcher to work under Dr. Oleg Larionov on total synthesis of trichodermamide natural products, photochemistry and organometallic chemistry. I started my graduate research at Georgia Tech in Dr. Kubanek’s lab from Spring 2017.
I am interested in the isolation and structure elucidation of bioactive natural products from marine organisms in search for novel drug leads. The process can entail wide variety of approaches in terms of analytical tools used (NMR, LC/MS, HPLC, IR, CD) along with chemical modifications and modeling studies using computation when necessary.
Chhetri BK, Lavoie S, Sweeney-Jones AM, Mojib N, Raghavan V, Gagaring K, Dale B, McNamara CW, Soapi K, Quave CL, Polavarapu PL, Kubanek J (2019) Peyssonnosides A-B, unusual diterpene glycosides with a sterically encumbered cyclopropane motif: structure elucidation using an integrated spectroscopic and computational workflow. The Journal of Organic Chemistry. 84 (13), 8531-8541. DOI: 10.1021/acs.joc.9b00884
Chhetri BK, Lavoie S, Sweeney-Jones AM, Kubanek J (2018) Recent trends in the structural revision of natural products. Natural Product Reports. 35 (6), 514-531. DOI: 10.1039/C8NP00011E
Mfuh, AM, Doyle JD, Chhetri B, Arman HD, Larionov OV (2016) Scalable, Metal-and Additive-Free, Photoinduced Borylation of Haloarenes and Quaternary Arylammonium Salts. Journal of the American Chemical Society. 138 (9), 2985-2988. DOI: 10.1021/jacs.6b01376
Mfuh AM, Nguyen VT, Chhetri B, Burch JE, Doyle JD, Nesterov VN, Arman HD, Larionov O V (2016) Additive-and Metal-Free, Predictably 1, 2-and 1, 3-Regioselective, Photoinduced Dual C–H/C–X Borylation of Haloarenes. Journal of the American Chemical Society. 138 (27), 8408-8411. DOI: 10.1021/jacs.6b05436
Stephens D E, Nguyen VT, Chhetri B, Clark ER, Arman HD, Larionov OV (2016) Organocatalytic Synthesis of Methylene-Bridged N-Heterobiaryls. Organic Letters. 18 (22), 5808-5811. DOI: 10.1021/acs.orglett.6b02719.