All organisms use chemicals to assess their environment and to communicate with others. Chemical cues for defense, mating, habitat selection, and food tracking are crucial, widespread, and structurally and functionally diverse. Yet our knowledge of chemical signaling is patchy, especially in marine environments. In our research we ask, “How do marine organisms use chemicals to solve critical problems of competition, disease, predation, and reproduction?” Our group uses an integrated approach to understand how chemical cues function in ecological interactions, working from molecular to community levels. We also use ecological insights to guide discovery of novel pharmaceuticals and molecular probes.

In collaboration with other scientists, our most significant scientific achievements to date are: 1) characterizing the unusual molecular structures of antimicrobial defenses that protect algae from pathogens and which show promise to treat human disease; 2) understanding that competition among single-celled algae (phytoplankton) is mediated by a complex interplay of chemical cues that affect harmful algal bloom dynamics; 3) unraveling the molecular modes of action of antimalarial natural products towards developing new treatments for drug-resistant infectious disease; 4) discovering that progesterone signaling and quorum sensing are key pathways in the alternating sexual and asexual reproductive strategy of microscopic invertebrate rotifers – animals whose evolutionary history was previously thought to preclude either cooperative behavior (quorum sensing) typically associated with bacteria and hormonal regulation via progesterone typically seen in vertebrates; 5) identifying a novel aversive chemoreception pathway in predatory fish that results in rapid recognition and rejection of chemically defended foods, thereby protecting these foods (prey) from predators.

Primary Investigator

Our Team

For web
Corporate headshot photography - Business photography

Ghada Abdelwahab

(Research Scientist)

Adetola Adewole

(Postdoctoral Researcher)

Nikki Aiosa

(Graduate Student) Co-Advised with Dr. Neha Garg

Gabi Chebli

(Graduate Student)

Benton Jaco

(Graduate Student)

Gretchen Johnson

(Graduate Student)


Shreya Kothari

(Graduate Student)

Maggie Straight

(Graduate Student)

Undergraduate Students

Past Lab Members

Ford Environmental Science & Technology Building

Address311 Ferst Dr NW, Atlanta, GA 30332
Phone(404) 894-2000